Short answer: The Evista label dose is one 60 mg tablet once daily, taken any time of day with or without meals. Calcium and vitamin D are added if diet falls short. Evista is stopped at least 72 hours before long immobilization. A missed dose is taken when remembered unless the next dose is near, and two doses are never taken at once.
This is what the FDA label says. Follow your prescriber. Your prescriber may use a different dose or pace than the label's standard schedule.
What Evista is approved for: Evista is an estrogen agonist/antagonist approved to treat and prevent osteoporosis in postmenopausal women, and to reduce the risk of invasive breast cancer in postmenopausal women with osteoporosis or at high risk of invasive breast cancer (sections 1.1 to 1.3). It is not approved to treat breast cancer, to lower the risk of it coming back, or to lower the risk of noninvasive breast cancer.
Source
EVISTA (raloxifene hydrochloride) tablet for oral use, prescribing information and Medication Guide. Eli Lilly and Company. DailyMed, version published September 2, 2026. DailyMed setid fcaaa6dc-74e8-4fb8-800c-5574bf0f8de9
Evista is one 60 mg tablet by mouth once daily, at any time of day, without regard to meals (section 2.1).
The Medication Guide says taking it at about the same time each day may help with remembering, and calcium and vitamin D may be taken at the same time.
For breast cancer risk reduction, the best length of treatment is not known (section 2.1).
The table below is the label's schedule, from the Dosage and Administration section. Numbers are copied exactly; the section is in brackets.
| Item | What the label says |
|---|---|
| Recommended dose | One 60 mg tablet daily |
| Timing and food | May be administered any time of day without regard to meals |
| Calcium | Postmenopausal women require an average of 1500 mg/day of elemental calcium; intake above 2000 mg has been associated with increased risk of adverse effects |
| Vitamin D | Recommended intake is 400-800 IU daily; some patients may need more |
| Length of use | For the breast cancer risk indications, the optimum duration of treatment is not known |
Evista is stopped at least 72 hours before and during long immobilization, such as recovery from surgery or long bed rest, and restarted only once fully walking. The Medication Guide says to stop at least 3 days before planned surgery.
Cholestyramine and other anion exchange resins are not taken with Evista, because they reduce its absorption.
With warfarin, prothrombin time is monitored more closely when Evista is started or stopped.
Breast exams and mammograms are done before starting and continued regularly during treatment.
No dose change is needed for older adults. Caution is used with liver impairment and moderate or severe kidney impairment (sections 8.6, 8.7).
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take only your next regularly scheduled dose. Do not take two doses at the same time.
More on this: missed a dose of Evista.
Evista is not used together with systemic estrogens, because the safety of the combination has not been established.
In Dose Track you set up Evista as a protocol with the dose and schedule your prescriber gave you. A protocol can hold dose steps, each with its own dose and length in days or weeks, so a step-up plan like the one on the label can be entered once and the app moves to the next step on its own. Reminders follow the schedule, and every dose is logged with the date and time, so you can see which step you are on and when your last dose was. The app follows what you enter; it does not choose or change a dose.
This page is what the FDA label says, in plain words. It is not medical advice. Follow your prescriber, and ask them or your pharmacist about anything here.