SR9009 (sold as stenabolic) is a synthetic small molecule, first described in 2012, that switches on REV-ERB, proteins that help run the body clock and metabolism. It is not a peptide or a SARM. It has been studied only in cells and animals and is not approved for human use.
Also known as: Stenabolic, SR-9009.
For SR9009, there is no approved product and no published human trial, so there are no label strengths or studied human amounts.
SR9009 is not approved, and we could not find any published study that gave it to people. WADA bans Rev-erb-alpha agonists, naming SR9009, banned in and out of competition under "metabolic modulators" (S4.4.1).
In the first paper (Solt 2012), REV-ERB agonists changed the daily rhythm of clock genes in mice, raised energy use, and in obese mice reduced fat mass and improved blood fats and blood sugar. A 2013 mouse study (Woldt) found that switching on Rev-erb-alpha increased exercise capacity. A 2019 study (Dierickx) found that SR9009 still changed cell survival, metabolism and gene activity in mouse cells that had no REV-ERB at all, so not all of its effects go through REV-ERB. Mouse results often do not carry over to people.
When researchers tested 44 products sold online as SARMs (Van Wagoner 2017), some contained SR9009.
We could not find a published human half-life or time to peak, so we do not list one. Figures quoted online usually come from animal studies.
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