Dihydrotestosterone (DHT, also called androstanolone or stanolone) is a natural androgen the body makes from testosterone using the 5-alpha-reductase enzyme. Unlike testosterone, it cannot be turned into estrogen. We found no DHT product approved for people in FDA's Drugs@FDA database.
Also known as: DHT, androstanolone, stanolone, 5α-dihydrotestosterone.
We found no DHT (androstanolone) product in FDA's Drugs@FDA database, so there are no US label strengths to list. The trials below used a gel rubbed on the skin.
DHT has no FDA label for people that we could find. Anabolic steroids are Schedule III controlled substances in the US, and this one is named in the federal list (21 CFR 1308.13(f)). Having it without a valid prescription is illegal. (It is listed there as 4-dihydrotestosterone.) WADA lists androstanolone (5α-dihydrotestosterone) as an anabolic steroid, banned in and out of competition when taken from outside the body.
In a 3-month randomized trial of DHT gel in 37 men aged 60 or older with lowish testosterone (Ly 2001), DHT lowered the body's own testosterone, LH and FSH, raised hemoglobin and red cells, and lowered total and LDL cholesterol and fat mass. Strength rose only in knee flexion, with no change in mobility, balance, thinking or quality of life. In a 2-year randomized trial in 114 healthy men over 50 (Idan 2010), DHT gel did not change prostate growth, but it lowered spine bone density by 1.4%, raised hemoglobin, and suppressed testosterone, estradiol, LH and FSH. Eight men stopped because of a high hematocrit, which went back to normal after stopping.
We found no FDA label for DHT, and the trial summaries we checked give no half-life or time to peak, so we do not list one.
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