ACOG issues long-awaited guidance on GLP-1 drugs in pregnancy and breastfeeding
The American College of Obstetricians and Gynecologists (ACOG) published a Practice Advisory for clinicians on GLP-1 drugs around pregnancy and breastfeeding.
- Before pregnancy: counsel that safety data are lacking; consider stopping 1-2 months before conception
- During pregnancy: advise against use
- Weight loss may raise fertility, so discuss reliable contraception
- Breastfeeding: shared decision-making; if used, closely monitor infant weight gain; advise against use with preterm infants and newborns
This is guidance built on limited human data, not new trial results. ACOG says it will update it as research emerges.
Source: Healio, Oct 23, 2026
