Short answer: Aldactone (spironolactone): store below 77°F (25°C); the label gives no lower limit and nothing else. Bystolic (nebivolol): store at 68° to 77°F (20° to 25°C), and pharmacies dispense it in a tight, light-resistant container. Its Patient Information says between 68° to 77°F (20° - 25°C). Neither label gives a fridge instruction.
| Question | Aldactone | Bystolic |
|---|---|---|
| Temperature | Below 77°F (25°C) | 20° to 25°C (68° to 77°F) |
| Lower limit or excursions | Not stated | Not stated |
| Light | Not stated | Dispense in a tight, light-resistant container |
| Pack | Bottles of 100 (25, 50 and 100 mg) | Bottles of 30, 90 and 100; 10 x 10 unit dose |
| Patient leaflet | None | Between 68° to 77°F (20° - 25°C) |
| Refrigerator | Not stated | Not stated |
Aldactone section 16: “Store below 77°F (25°C).” That is the whole storage text; there is no patient leaflet.
Bystolic section 16: “Store at 20° to 25°C (68° to 77°F) [see USP for Controlled Room Temperature].” “Dispense in a tight, light-resistant container as defined in the USP using a child-resistant closure.” Patient Information: “Store BYSTOLIC between 68° to 77°F (20° - 25°C).” “Safely throw away BYSTOLIC that is out of date or no longer needed.”
Dosing: Aldactone and Bystolic. Missed a dose: Aldactone and Bystolic. Side effects: Aldactone and Bystolic. Molecules: spironolactone and nebivolol.
No ice pack is needed. Keep both in their bottles in your carry-on and out of a hot car; Aldactone has an upper limit of 77°F (25°C), and Bystolic stays in its light-resistant bottle.