Short answer: Section 2.1 of the Oseni label says that if a dose is missed, do not double the next dose. The Medication Guide says take a missed dose as soon as you remember. If you do not remember until it is time for your next dose, skip the missed dose and take the next one at your regular time. Oseni is once daily.
| Situation | What the label says |
|---|---|
| Schedule | Once daily, with or without food; tablets not split (2.1); up to 25 mg alogliptin/45 mg pioglitazone (2.2) |
| Missed a dose | Take it as soon as you remember (Medication Guide) |
| Time for the next dose | Skip the missed dose; take the next at your regular time (Medication Guide) |
| Doubling up | Do not double the next dose (2.1, 17); do not take 2 doses at the same time (Medication Guide) |
Section 2.1: "If a dose is missed, do not double the next dose." Section 17: "Instruct patients if a dose is missed, not to double their next dose."
The Medication Guide says: "If you miss a dose, take it as soon as you remember. If you do not remember until it is time for your next dose, skip the missed dose and take the next dose at your regular time. Do not take 2 doses of OSENI at the same time."
No. Oseni contains pioglitazone, the Actos ingredient, but the leaflets differ. The Oseni Medication Guide says take a missed dose when you remember. The Actos Medication Guide says take your next dose as prescribed. Both say never two doses at once.
This page summarizes FDA labeling. It is not personalized medical advice; confirm what to do with your prescriber or pharmacist.