Controlled Substance Schedules: What CIII and CIV Mean
[Glossary · Quality, storage and rules]

Controlled substance schedule

Also called DEA schedule, CIII, CIV, Schedule III, Schedule IV, controlled substance · Reviewed

Definition: A controlled substance schedule is one of five groups, I to V, that US law (21 U.S.C. 812) uses to sort drugs by their potential for abuse, accepted medical use and risk of dependence. Labels print the schedule as a C with a Roman numeral, such as CIII or CIV.

The five schedules in the law

Findings for each schedule, from 21 U.S.C. 812(b), shortened
ScheduleAbuse potentialAccepted medical use
IHighNone in the US
IIHigh; may lead to severe dependenceYes, or with severe restrictions
IIILess than I and II; may lead to moderate or low physical or high psychological dependenceYes
IVLow relative to III; limited dependence relative to IIIYes
VLow relative to IV; limited dependence relative to IVYes

Schedules on labels on this site

Schedules printed on current US labels
ProductSchedule
Testosterone products such as Aveed and TestimCIII
Phendimetrazine tabletsCIII
Lomaira (phentermine)CIV
Diethylpropion tabletsCIV

The weight-loss labels say these drugs are related to amphetamine. See anorectic.

Why it matters for your log

A schedule is a legal category, not a measure of how well a drug works or how safe it is at a given dose. The law sets the findings for each schedule; the schedule of a specific product is printed on its package and label. The Lomaira label says selling or giving the drug away is against the law. Keeping your own log of each dose and refill gives you a clear record if a pharmacy or prescriber asks.

Read more on Dose Track: Aveed side effects · Testim side effects · Lomaira side effects · Phendimetrazine side effects

General education drawn from labels and published studies, not personal medical advice. Your prescriber, pharmacist and the label that came with your product are the final word.

Frequently asked questions

What does CIII mean on a label?+
It means the drug is in Schedule III under 21 U.S.C. 812: less abuse potential than Schedules I and II, with an accepted medical use. Testosterone products such as Aveed and Testim print CIII.
Is phentermine a controlled substance?+
Yes. The Lomaira label says phentermine is a Schedule IV controlled substance.