Short answer: The Lomaira label gives a usual adult dose of one 8 mg tablet three times a day, half an hour before meals, with the dose set to the lowest that works. The tablet is scored so half a tablet can be used. Lomaira is for short-term use (a few weeks), late evening doses are avoided because of insomnia, and the label has no missed-dose rule.
This is what the FDA label says. Follow your prescriber. Your prescriber may use a different dose or pace than the label's standard schedule.
What Lomaira is approved for: Lomaira is approved as a short-term (a few weeks) add-on to a weight-loss plan of exercise, behavior change and fewer calories, for obesity in people with a starting BMI of 30 kg/m2 or more, or 27 kg/m2 or more with other risk factors such as controlled high blood pressure, diabetes or high cholesterol (Indications and Usage). Phentermine is a Schedule IV controlled substance (Drug Abuse and Dependence).
Source
LOMAIRA (phentermine hydrochloride USP) tablets, 8 mg, CIV, prescribing information. KVK-Tech. DailyMed, version published December 20, 2023. DailyMed setid cde9fb09-e5af-434d-8874-e4f9f974d893
Lomaira is an 8 mg tablet of phentermine hydrochloride (6.4 mg phentermine base) taken by mouth. The tablet is scored so it can be split in half for people who do not need the full dose (Description, Dosage and Administration).
The usual adult dose is one tablet three times a day, half an hour before meals. The label says dosage should be individualized to the lowest effective dose, and late evening doses should be avoided because they may cause insomnia (Dosage and Administration).
Lomaira is approved only for short-term use, a few weeks, alongside exercise, behavior change and fewer calories (Indications and Usage).
The table below is the label's schedule, from the Dosage and Administration section. Numbers are copied exactly; the section is in brackets.
| Item | What the label says |
|---|---|
| Usual adult dose | One tablet (8 mg) three times a day, ½ hour before meals |
| Lower dose | Tablet is scored to give one half of the usual dosage for patients not requiring the full dose |
| Goal | Dosage individualized to obtain an adequate response with the lowest effective dose |
| Timing | Late evening medication should be avoided because of the possibility of resulting insomnia |
| Children | Not recommended for use in pediatric patients less than or equal to 16 years of age |
| Length of use | Short-term (a few weeks) |
If tolerance to the appetite effect develops, the recommended dose should not be exceeded to try to increase the effect; the drug should be stopped instead.
People with diabetes on insulin or oral diabetes medicines may need those doses lowered.
Lomaira is not used during or within 14 days after an MAOI, because of the risk of a hypertensive crisis.
In older adults, the label says dose selection should be cautious, usually starting at the low end of the range, and kidney function may be monitored.
With kidney impairment, phentermine levels are expected to rise, and caution is advised.
The smallest workable amount should be prescribed or dispensed at one time to limit the chance of overdose.
The Lomaira label gives no missed-dose instruction. It does say late evening doses should be avoided because of possible insomnia. Ask your prescriber or pharmacist what to do if a dose is missed.
Lomaira is approved only as monotherapy. Taking it with other weight-loss drugs, including prescription, over-the-counter and herbal products, or with SSRIs, is not recommended because safety and effectiveness have not been established.
In Dose Track you set up Lomaira as a protocol with the dose and schedule your prescriber gave you. A protocol can hold dose steps, each with its own dose and length in days or weeks, so a step-up plan like the one on the label can be entered once and the app moves to the next step on its own. Reminders follow the schedule, and every dose is logged with the date and time, so you can see which step you are on and when your last dose was. The app follows what you enter; it does not choose or change a dose.
This page is what the FDA label says, in plain words. It is not medical advice. Follow your prescriber, and ask them or your pharmacist about anything here.