Short answer: The Admelog label gives each dose under the skin within fifteen minutes before a meal or immediately after a meal, usually alongside an intermediate or long-acting insulin. The dose is set for each person. Switching from another insulin lispro product uses the same dose. In a pump, the reservoir is changed at least every 7 days. The label has no missed-dose rule.
This is what the FDA label says. Follow your prescriber. Your prescriber may use a different dose or pace than the label's standard schedule.
What Admelog is approved for: Admelog is a rapid-acting mealtime insulin approved to improve blood sugar control in adults and children with diabetes (section 1).
Source
ADMELOG (insulin lispro) injection, for subcutaneous or intravenous use, prescribing information, Patient Information and Instructions for Use. Sanofi-Aventis U.S.. DailyMed, version published June 25, 2025. DailyMed setid 0691def8-4a7b-4de3-866f-a280989f47f1
Admelog is injected under the skin of the abdominal wall, thigh, upper arm or buttocks within fifteen minutes before a meal or immediately after a meal, rotating sites within the same region. By injection it is generally used with an intermediate or long-acting insulin (section 2.2).
It can also be given by insulin pump, following the pump's instructions, or into a vein only under medical supervision. It is U-100 (100 units/mL) in 10 mL and 3 mL multiple-dose vials and a 3 mL SoloStar pen that dials in 1-unit steps (sections 2.2 and 3).
The table below is the label's schedule, from the Dosage and Administration section. Numbers are copied exactly; the section is in brackets.
| Situation | What the label says |
|---|---|
| When to inject | Within fifteen minutes before a meal or immediately after a meal |
| Dose | Individualized by route, metabolic needs, glucose monitoring and glucose goal |
| Switching from another insulin lispro product | Same dose as the other insulin lispro product |
| Switching from other insulins | The dose may need adjusting |
| Diluting for injection under the skin | One part Admelog to one part 0.9% sodium chloride (equivalent to U-50); use within 24 hours refrigerated or 4 hours at room temperature |
| Pump reservoir | Change at least every 7 days, or per the pump manual if shorter; not diluted or mixed |
| IV infusion | Diluted to 0.1 to 1 unit/mL, under medical supervision with glucose and potassium monitoring |
| Presentation | Unopened, room temp up to 86 F | Unopened, refrigerated 36-46 F | In use (opened) |
|---|---|---|---|
| 10 mL multiple-dose vial | 28 days | Until expiration date | 28 days, refrigerated or room temperature |
| 3 mL multiple-dose vial | 28 days | Until expiration date | 28 days, refrigerated or room temperature |
| 3 mL SoloStar pen | 28 days | Until expiration date | 28 days at room temperature; do not refrigerate |
Dose changes may be needed with changes in activity, meals, kidney or liver function, or during acute illness. Glucose is checked more often during any change to the insulin regimen.
The dose may need changing when Admelog is used with certain other drugs. Section 2.4 says Admelog is not mixed with any other insulin; section 2.1 says it is not mixed with other insulins in a pump.
Pump users are trained to inject insulin and keep backup insulin in case of pump failure. Admelog in a pump reservoir is not exposed to temperatures above 98.6 F (37 C).
Admelog is never frozen and is not used if it has been, and is protected from direct heat and light. Opened vials and pens are used within 28 days or thrown away, even if insulin is left.
The Admelog label gives no missed-dose rule. Neither the prescribing information nor the Patient Information says what to do if a dose is missed; the Patient Information says your healthcare provider should tell you how much Admelog to use and when.
From another insulin lispro product, the Admelog dose is the same. From other insulins, the Admelog dose may need adjusting.
Any change of insulin strength, maker, type, site or method is made under close medical supervision with more frequent glucose checks.
In Dose Track you set up Admelog as a protocol with the dose and schedule your prescriber gave you. A protocol can hold dose steps, each with its own dose and length in days or weeks, so a step-up plan like the one on the label can be entered once and the app moves to the next step on its own. Reminders follow the schedule, and every dose is logged with the date and time, so you can see which step you are on and when your last dose was. The app follows what you enter; it does not choose or change a dose.
This page is what the FDA label says, in plain words. It is not medical advice. Follow your prescriber, and ask them or your pharmacist about anything here.