DNP (2,4-Dinitrophenol): Poisoning Risk and Status
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DNP (2,4-Dinitrophenol): poisoning risk and status

US status · Approval status · Half-life notes

What is DNP?

DNP (2,4-dinitrophenol) is a toxic industrial chemical that some people take to lose body fat. It works by making cells burn energy as heat instead of storing it, and the same action can push body temperature dangerously high. It is not an approved medicine for people.

Also known as: 2,4-dinitrophenol, dinitrophenol.

US products

DNP is not an approved drug, so there are no label strengths. We do not list any amounts for DNP.

Approval status and how it is used

We found no DNP product in FDA's Drugs@FDA database. WADA names 2,4-dinitrophenol on its Prohibited List under "non-approved substances" (S0), banned at all times.

DNP poisoning is often fatal. In 204 cases reported to UK and US poison centres in 2007 to 2018 (Potts 2021), about 12% of US cases and 17% of UK cases died; 86% of people were under 40. Signs linked to death were acidosis, a fast heart rate, agitation or confusion, and a very high temperature. A survey of poison centres in 38 countries found 456 cases from 2010 to 2020, with about 12% fatal and no difference between men and women (Gziut 2022).

Anyone who has taken DNP and feels hot, sweaty, confused or has a racing heart needs emergency care right away. In the US, Poison Control is 1-800-222-1222.

DNP half-life and time to peak

  • Half-lifeNot listed
  • Time to peak (Tmax)Not listed

We do not list a half-life or time to peak for DNP. The poison-centre studies we cite describe its toxicity, not its timing.

How to track DNP in Dose Track

  1. Add DNP as a custom compound. Start typing its name and Dose Track fills in the details from its research library for you to check, and it sits next to everything else you take.
  2. Log each dose when you take it so your history shows exactly what you took and when.
  3. Set reminders on your own schedule, whether that is daily, weekly or every few days.
  4. Your log is stored on your phone and no account is needed. Data only leaves it for features you choose, like AI answers and lab reading.

How Dose Track handles peptides · Reconstitution calculator · Half-life calculator

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Frequently asked questions

What is the half-life of DNP?+
We do not list a half-life or time to peak for DNP. The poison-centre studies we cite describe its toxicity, not its timing.
Is DNP legal?+
It is not an approved medicine for people; we found no DNP product in Drugs@FDA. It is sold as an industrial chemical. WADA bans it in sport at all times.
How dangerous is DNP?+
Very. In cases reported to UK and US poison centres, about 12% to 17% of people died (Potts 2021), and a 38-country survey found about 12% of cases were fatal (Gziut 2022). There is no safe amount we can point to.
Can I track DNP in Dose Track?+
Yes. DNP is in Dose Track's research library, so when you add it as a custom compound its details are filled in for you to check. You can then log each dose next to your other compounds, set reminders on your own schedule, and see your history next to your lab results. Your log is stored on your phone and no account is needed. Data only leaves it for features you choose, like AI answers and lab reading.

Sources

  1. Potts AJ, et al. Toxicoepidemiology and predictors of death in 2,4-dinitrophenol (DNP) toxicity. Clin Toxicol (Phila). 2021;59(6):515-520.
  2. Gziut T, Thomas SHL. International trends in systemic human exposures to 2,4 dinitrophenol reported to poisons centres. Clin Toxicol (Phila). 2022;60(5):628-631.
  3. World Anti-Doping Agency. 2026 Prohibited List (S0 non-approved substances; S1 anabolic agents; S4.1 aromatase inhibitors; S4.4.1 metabolic modulators).

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