ACP-105 (SARM): What It Is, Rat Study and Status
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ACP-105: what it is, rat study and status

Amounts studied · Approval status · Half-life notes

What is ACP-105?

ACP-105 is a non-steroidal selective androgen receptor modulator (SARM) discovered by Acadia Pharmaceuticals. It is a partial activator of the androgen receptor, has been studied only in animals, and is not FDA approved.

Also known as: ACP105.

Amounts studied

For ACP-105, there is no approved product and no published human trial, so there are no label strengths or studied human amounts.

Approval status and how it is used

ACP-105 is not FDA approved, and we could not find any published trial that gave it to people. FDA says SARMs are unapproved drugs that cannot be legally marketed in the US as dietary supplements or drugs, and lists risks including liver injury and acute liver failure, a higher risk of heart attack or stroke, and effects on fertility. WADA bans SARMs as a class under "other anabolic agents" (S1.2), in and out of competition; its 2026 list names several SARMs as examples, and the class is not limited to the ones it names.

Its developers reported that it improved anabolic measures in a 2-week study in castrated male rats (Schlienger 2009). Rat results often do not carry over to people. An anti-doping lab described ACP-105 as a drug candidate without clinical approval and set out how to detect it in doping tests (Thevis 2013).

ACP-105 half-life and time to peak

  • Half-lifeNot listed
  • Time to peak (Tmax)Not listed

We could not find a published human half-life or time to peak, so we do not list one. Figures quoted online usually come from animal studies or computer models.

How to track ACP-105 in Dose Track

  1. Add ACP-105 as a custom compound. Start typing its name and Dose Track fills in the details from its research library for you to check, and it sits next to everything else you take.
  2. Log each dose when you take it so your history shows exactly what you took and when.
  3. Set reminders on your own schedule, whether that is daily, weekly or every few days.
  4. Your log is stored on your phone and no account is needed. Data only leaves it for features you choose, like AI answers and lab reading.

How Dose Track handles peptides · Reconstitution calculator · Half-life calculator

AC-262536AC-262,536, AC262536 RAD-140 (Testolone)RAD140, Testolone · half-life about 45 hours Ostarine (Enobosarm)enobosarm, MK-2866 Ligandrol (LGD-4033)LGD-4033, VK5211 · half-life about 30 hours

Frequently asked questions

What is the half-life of ACP-105?+
We could not find a published human half-life or time to peak, so we do not list one. Figures quoted online usually come from animal studies or computer models.
Has ACP-105 been tested in people?+
Not in any published trial we could find. The research is a 2-week rat study (Schlienger 2009), anti-doping detection work and computer models.
Can I track ACP-105 in Dose Track?+
Yes. ACP-105 is in Dose Track's research library, so when you add it as a custom compound its details are filled in for you to check. You can then log each dose next to your other compounds, set reminders on your own schedule, and see your history next to your lab results. Your log is stored on your phone and no account is needed. Data only leaves it for features you choose, like AI answers and lab reading.

Sources

  1. FDA Consumer Update. FDA warns of use of selective androgen receptor modulators (SARMs) among teens, young adults (April 2023).
  2. World Anti-Doping Agency. 2026 Prohibited List (S0 non-approved substances; S1 anabolic agents; S4.1 aromatase inhibitors; S4.4.1 metabolic modulators).
  3. Schlienger N, et al. Synthesis, structure-activity relationships, and characterization of novel nonsteroidal and selective androgen receptor modulators. J Med Chem. 2009;52(22):7186-7191.
  4. Thevis M, et al. Expanding sports drug testing assays: mass spectrometric characterization of the selective androgen receptor modulator drug candidates RAD140 and ACP-105. Rapid Commun Mass Spectrom. 2013;27(11):1173-1182.

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