Short answer: Finasteride 1 mg (Propecia) is FDA approved for male pattern hair loss; saw palmetto is an herbal supplement that is not.12 In one open 2-year study of 100 men, hair improved in 68% on finasteride vs 38% on saw palmetto 320 mg.3 For enlarged prostate, a Cochrane review found saw palmetto alone did little more than placebo.4
| Saw palmetto | Finasteride (Propecia) | |
|---|---|---|
| What it is | Berry extract of a small palm, sold as a supplement2 | 5-alpha-reductase inhibitor tablet1 |
| FDA approved for hair loss | No2 | Yes, men only1 |
| Amount used | Hair study: 320 mg a day3 | Label: 1 mg once a day1 |
| Hair study, 2 years | Improved in 38%3 | Improved in 68%3 |
| Time to judge | Not set | Usually 3 months or more of daily use; benefit reverses within 12 months of stopping1 |
| Effect on PSA | Does not appear to change PSA2 | Lowers PSA1 |
| Side effects | Mild and infrequent: digestive symptoms, dizziness, headache2 | Year 1: decreased libido 1.8% vs 1.3% on placebo; erectile dysfunction 1.3% vs 0.7%1 |
| Pregnancy | May be unsafe2 | Contraindicated; women who may be pregnant should not handle broken tablets1 |
Yes, in one open-label study. 100 men with mild to moderate male pattern hair loss took saw palmetto 320 mg or finasteride 1 mg every day for 24 months. Judged from photos, 38% on saw palmetto and 68% on finasteride had more hair. The authors noted finasteride helped both the front and the crown, while saw palmetto helped mostly the crown.3
Open-label means everyone knew what they were taking, and there was no placebo group. NCCIH says the evidence for saw palmetto in hair loss is too limited to draw conclusions.2 These are study protocols, not personalized advice; confirm any dosing with your prescriber.
Finasteride 5 mg is a different product for BPH; Propecia 1 mg is for hair. A 1996 six-month double-blind trial of 1,098 men compared a saw palmetto extract (Permixon 320 mg) with finasteride 5 mg. Symptom scores fell 37% and 39%. Finasteride shrank the prostate by 18% and lowered PSA by 41%; the extract shrank it 6% and did not change PSA. Its first author worked for the extract's maker.5
Later placebo-controlled research is less positive. A 2023 Cochrane review of 27 studies with 4,656 men found that saw palmetto alone makes little to no difference to urinary symptoms compared with placebo (high-certainty evidence).4
More detail: Propecia side effects, the Propecia dosing schedule, and the Saw Palmetto (Serenoa repens) and Finasteride guides.