Missed a Cytomel Dose? What to Do Now | Dose Track
[Missed dose · Cytomel]

I missed my Cytomel dose. What should I do?

liothyronine sodium (T3) tablets · Taken by mouth once daily · Label checked

Short answer: The Cytomel label has no missed-dose instructions. It describes tablets taken by mouth once daily, usually 25 to 75 mcg for adults with hypothyroidism. Liothyronine (T3) has a biological half-life of about 2 and a half days, shorter than levothyroxine, but a single missed tablet still lowers levels gradually. Ask your prescriber or pharmacist what to do.

What does the Cytomel label say about missed doses?

From the FDA label on DailyMed. Numbers in brackets are label section numbers.
SituationWhat the label says
ScheduleOnce daily by mouth (2.1); usual adult maintenance 25 to 75 mcg (2.2)
Missed-dose ruleNone in the label
Half-lifeAbout 2 and a half days (12.3)
Heart symptomsDose reduced or held for one week, then restarted lower (5.1)

Does the Cytomel label say what to do if I miss a dose?

No. We checked the Cytomel prescribing information from Pfizer on DailyMed. It has no missed-dose section and no separate patient leaflet. Section 2.1 says Cytomel is taken by mouth once daily, with the dose set for each person and adjusted from checkups and lab tests.

How long does a Cytomel dose last?

Section 12.3 says the biological half-life is about 2 and a half days. It also says levothyroxine (T4) binds more tightly to blood proteins than T3, which partly explains T4's longer half-life. So T3 levels move faster than T4 levels, but they still do not drop to zero in a day.

This page summarizes FDA labeling. It is not personalized medical advice; confirm what to do with your prescriber or pharmacist.

Missed-dose rules for other medicines

Frequently asked questions

What happens if I miss a dose of Cytomel?+
The Cytomel label has no missed-dose instruction. Ask your prescriber or pharmacist what to do.
How long does liothyronine stay in your system?+
Section 12.3 gives a biological half-life of about 2 and a half days.
Can I take an extra Cytomel tablet to catch up?+
The label does not describe catch-up doses. Ask your prescriber or pharmacist before taking more than your usual dose.