Passionflower: Anxiety, Sleep and Surgery Cautions
[Supplement · Compound guide]

Passionflower: half-life, strengths and approval status

Status · Approval status · Half-life notes

What is passionflower?

Passionflower (Passiflora incarnata) is a climbing vine traditionally used as a sedative and sold for anxiety, sleep and stress. NCCIH says a small amount of research suggests it might reduce anxiety, but conclusions are not definite.

Also known as: Passiflora incarnata, passiflora, maypop.

Amounts studied

NCCIH says passionflower tea may be safe for up to 7 nights and daily extract for up to 8 weeks; studies used different preparations, so we do not list an amount.

Approval status and how it is used

It is sold in the US as a dietary supplement. Under the 1994 dietary supplement law (DSHEA), FDA does not approve dietary supplements before they are marketed, and the maker, not FDA, is responsible for safety and labeling.

What studies show, per NCCIH: a small amount of research suggests oral passionflower might reduce anxiety, including anxiety before surgery or dental work, and might improve total sleep time in adults with insomnia, with mixed effects on falling and staying asleep. There is not enough evidence for ADHD, menopause symptoms, fibromyalgia, stress or other uses. A 2007 Cochrane review found only 2 trials (198 people), too few to draw conclusions; one found no difference between passionflower and a benzodiazepine (Miyasaka 2007).

Safety, per NCCIH: possible side effects include drowsiness, dizziness and confusion. Taken with anesthesia or other medicines used around surgery, it might slow down the nervous system too much; tell your clinician if you take it within 2 weeks of a planned surgery. It should not be used in pregnancy because it may cause uterine contractions, and little is known about breastfeeding.

Passionflower half-life and time to peak

  • Half-lifeNot listed
  • Time to peak (Tmax)Not listed

We could not find a single published half-life or time to peak for passionflower that applies to a supplement dose, so we do not list one. Plant extracts are mixtures of many compounds, so no single figure would describe them.

How to track passionflower in Dose Track

  1. Add passionflower as a custom compound. Start typing its name and Dose Track fills in the details from its research library for you to check, and it sits next to everything else you take.
  2. Log each dose when you take it so your history shows exactly what you took and when.
  3. Set reminders on your own schedule, whether that is daily, weekly or every few days.
  4. Your log is stored on your phone and no account is needed. Data only leaves it for features you choose, like AI answers and lab reading.

How Dose Track handles peptides · Reconstitution calculator · Half-life calculator

Frequently asked questions

What is the half-life of passionflower?+
We could not find a single published half-life or time to peak for passionflower that applies to a supplement dose, so we do not list one. Plant extracts are mixtures of many compounds, so no single figure would describe them.
Does passionflower help anxiety?+
Possibly, but the evidence is small. NCCIH says a small amount of research suggests it might reduce anxiety, and a Cochrane review found too few trials to draw conclusions.
Can I take passionflower before surgery?+
Talk to your clinician first. NCCIH says it might slow the nervous system too much when combined with anesthesia or other surgery medicines, and to tell your provider if you take it within 2 weeks of a scheduled surgery.
Can I track passionflower in Dose Track?+
Yes. Passionflower is in Dose Track's research library, so when you add it as a custom compound its details are filled in for you to check. You can then log each dose next to your other compounds, set reminders on your own schedule, and see your history next to your lab results. Your log is stored on your phone and no account is needed. Data only leaves it for features you choose, like AI answers and lab reading.