Olive leaf extract is made from the leaves of the olive tree and is rich in phenolic compounds such as oleuropein. It is taken for heart and metabolic health, mainly blood pressure, cholesterol and blood sugar.
Also known as: olive leaf, Olea europaea leaf, oleuropein, OLE.
An 8-week placebo-controlled trial used 500 mg a day (Stevens 2021). These are study protocols, not a recommendation.
It is sold in the US as a dietary supplement. Under the 1994 dietary supplement law (DSHEA), FDA does not approve dietary supplements before they are marketed, and the maker, not FDA, is responsible for safety and labeling.
What studies show: a 2024 review of 12 trials (703 adults, 2 days to 12 weeks long) found some trials linking olive leaf extract with better blood sugar, blood pressure, cholesterol or inflammation, but in the pooled analysis fasting blood sugar, in studies using a low dose, favored the control group, and the reviewers say more consistent studies are needed (Álvares 2024). In a placebo-controlled trial of 77 adults with overweight and mildly high cholesterol, 500 mg a day for 8 weeks did not change cholesterol, blood pressure, blood sugar, insulin or liver tests (Stevens 2021). The first author of that trial is employed by BioActor BV.
Safety: no differences in liver tests were found in the 8-week trial (Stevens 2021). The sources here do not describe drug interactions.
We could not find a single published half-life or time to peak for olive leaf extract that applies to a supplement dose, so we do not list one. Plant and bee products are mixtures of many compounds, so no single figure would describe them.
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