Livagen is a synthetic four-amino-acid peptide (Lys-Glu-Asp-Ala, also called KEDA) from the same Russian research group as Epitalon. Its developers describe it as a bioregulator for the liver. It is not approved as a drug in the US, and human evidence is very limited.
Also known as: Lys-Glu-Asp-Ala, KEDA peptide.
Livagen powder vials are usually labeled 20 mg.
Water and syringe-unit charts by vial size: 20 mg
Here is the math for a 20 mg vial mixed with 2 mL of bacteriostatic water, drawing 1 mg with a U-100 insulin syringe (1 mL = 100 units).
20 mg ÷ 2 mL = 10 mg/mL1 mg ÷ 10 mg/mL = 0.1 mL0.1 mL × 100 = 10 units| Amount | Volume | U-100 syringe |
|---|---|---|
| 500 mcg | 0.05 mL | 5 units |
| 1 mg | 0.1 mL | 10 units |
| 2 mg | 0.2 mL | 20 units |
Adding more water doesn't change how much livagen is in the vial. It only spreads it over more liquid, so each draw is bigger and easier to read.
| Water added | Concentration | Volume | U-100 syringe |
|---|---|---|---|
| 1 mL | 20 mg/mL | 0.05 mL | 5 units |
| 2 mL | 10 mg/mL | 0.1 mL | 10 units |
| 3 mL | 6.67 mg/mL | 0.15 mL | 15 units |
| 5 mL | 4 mg/mL | 0.25 mL | 25 units |
For any other vial size or amount, the free peptide reconstitution calculator works backwards from the amount you want and suggests a water volume that lands on a clean syringe mark.
In lab dishes, livagen loosened tightly packed chromatin in white blood cells from older people (Khavinson 2002; Lezhava 2007, donors aged 80 to 91). In rats, two weeks by mouth lowered digestive enzyme activity in young animals and raised it in old ones (Timofeeva 2005). A 2020 review by its developers reports liver-protective effects in animal models of hepatitis and cirrhosis (Kuznik 2020).
We could not find a published clinical trial of livagen in people.
We could not find a published human half-life for this compound. Figures quoted online usually come from animal or cell studies, so we do not list one here.
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