Fadogia agrestis is a plant used in traditional African medicine for pain, inflammation and as an aphrodisiac. It is sold in dietary supplements; the research on testosterone is in rats, not people.
Also known as: Fadogia.
There are no human studies or reference amounts. The rat studies gave 18, 50 or 100 mg of stem extract per kg of body weight by mouth (Yakubu 2005, 2008, 2009). These are animal study doses, not a recommendation.
It is sold in the US as a dietary supplement. Under the 1994 dietary supplement law (DSHEA), FDA does not approve dietary supplements before they are marketed, and the maker, not FDA, is responsible for safety and labeling.
What studies show (all in male rats): over 5 days, the extract raised blood testosterone and mating behavior (Yakubu 2005). But 28 days at the same doses changed several measures of testicular function in ways the authors called adverse, with only partial recovery at the lowest dose (Yakubu 2008), and caused signs of cell damage in the liver and kidney (Yakubu 2009).
Label testing: when University of Mississippi researchers tested 17 supplements claiming to contain Fadogia agrestis, 5 had none of the plant's marker compounds (Avula 2019). We found no human trials of Fadogia, so its effects and safety in people are unknown.
We could not find a single published half-life or time to peak for Fadogia agrestis that applies to a supplement dose, so we do not list one. Herbal products are mixtures of many plant compounds, so no single figure would describe them. It has not been studied in people.
How Dose Track handles peptides · Reconstitution calculator · Half-life calculator