Chlorophyllin is a water-soluble mix made from chlorophyll, the green pigment in plants, usually with copper and sodium. Most "chlorophyll" supplements and liquid drops contain chlorophyllin rather than natural chlorophyll.
Also known as: chlorophyll, liquid chlorophyll, sodium copper chlorophyllin, CHL.
A liver-cancer prevention trial used 100 mg three times a day for 4 months (Egner 2001); an odor trial used 100 mg a day for 2 weeks (Nahata 1983). These are study protocols, not a recommendation.
The NIH Dietary Supplement Label Database lists chlorophyllin products such as Chlorophyllin 100 mg from Life Extension as a dietary supplement. Under the 1994 dietary supplement law (DSHEA), FDA does not approve dietary supplements before they are marketed, and the maker, not FDA, is responsible for safety and labeling. The 2001 trial describes chlorophyllin as a food colorant and an over-the-counter medicine (Egner 2001).
What studies show: in a placebo-controlled trial in 180 adults in Qidong, China, where food often contains aflatoxin (a mold toxin linked to liver cancer), chlorophyllin at each meal for 4 months cut a urine marker of aflatoxin DNA damage by 55%. It did not measure cancer itself (Egner 2001). In a crossover trial in 20 older adults with urinary catheters, 100 mg a day for 2 weeks did not reduce urine odor more than placebo (Nahata 1983). A 2026 first-in-human study in healthy men found doses up to 3,000 mg were well tolerated (Patwardhan 2026). We found no human trials of the skin, weight or "detox" claims often made for it.
Safety: no side effects were reported in the 4-month trial (Egner 2001). The sources here do not describe drug interactions.
We could not find a single published half-life or time to peak for chlorophyllin that applies to a supplement dose, so we do not list one.
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