Calendula is the flower of the pot marigold (Calendula officinalis). It is used mainly in creams, ointments and mouth rinses for minor skin and mouth inflammation.
Also known as: marigold, pot marigold, Calendula officinalis, calendula cream.
Calendula is mostly used on the skin, and the trials used different creams and extracts, so we do not list one amount.
In the EU, EMA concluded that calendula flower preparations can be used for minor skin inflammation such as sunburn, to help minor wounds heal (from age 6), and for minor mouth or throat inflammation (from age 12). EMA bases this on long-standing ("traditional") use: there is not enough evidence from clinical trials, but the effect is plausible and the herb has been used safely this way for at least 30 years, including at least 15 years in the EU. EMA said clinical studies on leg ulcers, burns and skin inflammation had design problems, so no firm conclusions could be drawn (EMA).
What studies show: a 2019 systematic review found some evidence for faster healing of acute wounds and two controlled studies of smaller venous ulcers, but no benefit in a burn trial or a diabetic leg ulcer trial (Givol 2019). For skin damage from breast cancer radiotherapy, one earlier trial favored calendula over trolamine while another found no benefit (Givol 2019); a 2021 trial in 81 women found no difference from a standard moisturizer, though it was underpowered (Siddiquee 2021).
Safety: EMA says skin allergy has been reported, and calendula should not be used by people allergic to plants in the daisy family (Asteraceae). The sources here do not describe drug interactions.
We could not find a single published half-life or time to peak for calendula that applies to a supplement dose, so we do not list one. Plant extracts are mixtures of many compounds, so no single figure would describe them.
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